Cognitive Performance in Schizophrenic Inpatients: Are there Differential Effects within Antipsychotics?

Abstract

Objective: The cognitive performance of schizophrenic inpatients has been investigated considering antipsychotic treatment and compared to depressive controls. Methods: Cognitive function and mental state of schizophrenic (n=66) and depressive (n=47) inpatients were assessed. Results: The performance of the schizophrenic group was significantly worse compared to the depressive group in all cognitive functions. Schizophrenic inpatients treated with Pali-peridone were superior in memory tasks, patients treated with Olanzapine performed better in executive functions. Conclusions: Although causal relationships cannot be drawn results point to pharmacodifferential effects on cognitive functions within antipsychotics.